Published Work

6. Immune-Modulating Photochromic Galactosyl Ceramides allow for Optical Control of 

    Cytokine Production

N. Hartrampf, T, Seki, A. Baumann, P. Watson, N. Vepcek, B. Hetzler, A. Hoffmann-Röder, M. Tsuji, D. Trauner, Chem. Eur. J. 2019, DOI: 10.1002/chem.201905279.

5. Protein Chemistry Looking Ahead

C. Bello, N. Hartrampf, L. J. Walport, A. C. Conibear, Cell Chem. Biol. 2019, 26, 1349-1354.

4. Total Synthesis of the Norhasubanan Alkaloid Stephadiamine

N. Hartrampf, N. Winter, G. Pupo, B. Stoltz, D. Trauner, J. Am. Chem. Soc. 2018, 140, 8675-8680;

Highlighted in Synfacts: E. M. Carreira, F. Pultar, Synfacts 2018, 14, 0898.

3. Light control of L-type Ca2+ channels using a diltiazem photoswitch

T. Fehrentz,  F. M. E. Huber, N. Hartrampf, T. Bruegmann, J. A. Frank, N. H. F. Fine, D. Malan, J. G. Danzl, D. B. Tikhonov, M. Sumser, P. Sasse, D. J. Hodson, B. S. Zhorov, N. Klöcker, D. Trauner, Nat. Chem. Biol. 2018, 14, 764–767.

Highlighted in Nature Chemical Biology News & Views: V. Vendrell, Nat. Chem. Bio 2018, 14, 749–750.

2. Synthetic Approaches towards Alkaloids Bearing alpha-Tertiary Amines

A. Hager,‡ N. Vrielink, ‡ D. Hager, J. Lefranc, D. Trauner, Nat. Prod. Rep. 2016, 33, 491–522. (‡ = authors contributed equally)

1. Targeting a Dynamic Protein–Protein Interaction: Fragment Screening against the

   Malaria Myosin A Motor Complex

C. H. Douse, N. Vrielink, Z. Wenlin, E. Cota, E. W. Tate, ChemMedChem 2015, 10, 134–143.

11. AUTOMATED FAST-FLOW SYNTHESIS OF ANTISENSE PHOSPHORODIAMIDATE

    MORPHOLINO OLIGOMERS

C. Li,‡ A. J. Callahan,‡ M. D. Simon, K. A. Totaro, A. J. Mijalis, N. Hartrampf, C. K. Schissel. M. Zhou, H. Zong, G. J. Hanson, A. Loas, N. L. B. Pohl. B. L. Pentelute, submitted for publication. (‡ = authors contributed equally)

Preprint on ChemRxiv (DOI: 10.26434/chemrxiv.12685886.v1, link)

12. FLOW‐BASED SPPS FOR PROTEIN SYNTHESIS: A PERSPECTIVE

Z. P. Gates, N. Hartrampf

Pep. Sci. 2020, e24198. (link)

10. DEEP LEARNING FOR PREDICTION AND OPTIMIZATION OF FAST-FLOW

    PEPTIDE SYNTHESIS

S. Mohapatra,‡ N. Hartrampf,‡ M. Poskus, A. Loas R. Gomez-Bombarelli, B. L. Pentelute, submitted for publication. (‡ = authors contributed equally)

Preprint on ChemRxiv (DOI: 10.26434/chemrxiv.12649343.v1, link)

9. ULTRA-LARGE CHEMICAL LIBRARIES FOR THE DISCOVERY OF HIGH-AFFINITY

    PEPTIDE BINDERS

A. J. Quartararo, Z. P. Gates, B. A. Somsen, N. Hartrampf, X. Ye, A. Shimada, Y. Kajihara, C. Ottmann, B. L. Pentelute

Nat. Commun. 2020, 11, 3183 (link)

8. SYNTHESIS OF PROTEINS BY AUTOMATED FLOW CHEMISTRY

N. Hartrampf, A. Saebi,‡ M. Poskus,‡ Z. P. Gates, A. J. Callahan, A. E. Cowfer, S. Hanna, S. Antilla, C. K. Schissel, A. J. Quartararo, X. Ye, A. J. Mijalis, M. D. Simon, A. Loas, S. Liu, C. Jessen, T. E. Nielsen, B. L. Pentelute (‡ = authors contributed equally)

Science 2020, 368, 980-987. (link)

Highlighted in a Science Perspective: C. Proulx, Science 2020, 368, 941 (link)

and by MIT News (link), Chemistry World (link), CE&N (link), Science Daily (link), Drug Target Review (link), Phys Org (link), the American Peptide Society (link) and others.