Published Work
ORCID-ID: 0000-0003-0875-6390
6. Immune-Modulating Photochromic Galactosyl Ceramides allow for Optical Control of
Cytokine Production
5. Protein Chemistry Looking Ahead
4. Total Synthesis of the Norhasubanan Alkaloid Stephadiamine
3. Light control of L-type Ca2+ channels using a diltiazem photoswitch
Highlighted in Nature Chemical Biology News & Views: V. Vendrell, Nat. Chem. Bio 2018, 14, 749–750.
2. Synthetic Approaches towards Alkaloids Bearing alpha-Tertiary Amines
1. Targeting a Dynamic Protein–Protein Interaction: Fragment Screening against the
Malaria Myosin A Motor Complex
PUBLISHED WORK
ORCID-ID: 0000-0003-0875-6390
15. AUTOMATED FAST-FLOW SYNTHESIS OF PEPTIDE NUCLEIC ACID CONJUGATES
C. Li, A. J. Callahan, K.-S. Phadke, B. Bellaire, C. E. Farquhar, G. Zhang, C. K. Schissel, A. J. Mijalis, N. Hartrampf, A. Loas, D. E. Verhoeven, B. Pentelute
Preprint on ChemRxiv (https://doi.org/10.26434/chemrxiv.14099042.v1 link)
14. TARGETING GLIOBLASTOMA USING A NOVEL PEPTIDE SPECIFIC TO A
DEGLYCOSYLATED ISOFORM OF BREVICAN
N. v. Spreckelsen, C. M. Fadzen, N. Hartrampf, Y. Ghotmi, J. M. Wolfe, S. Dubey, B. Y. Yang, M. F. Kijewski, S. Wang, C. Farquhar, S. Bergmann, M. Zdioruk, J. R. Wasserburg, B. Scott, E. Murrell, F. C. Bononi, L. G. Luyt, M. DiCarli, M. L. M. Lamfers, K. L. Ligon, E. A. Chiocca, M. S. Viapiano, B. L. Pentelute, S. E. Lawler, C.-F. Cho
Adv. Ther. 2021, (link)
13. IDENTIFICATION OF N-TERMINALLY DIVERSIFIED GLP-1R AGONISTS
USING SATURATION MUTAGENESIS AND CHEMICAL DESIGN
C. K. Longwell, S. Hanna, N. Hartrampf, R. A. P. Sperberg, P.-S. Huang, B. L. Pentelute, J. R. Cochran
ACS Chem. Bio. 2020, 16, 58–66; ACS Editors' Choice (link)
12. FLOW‐BASED SPPS FOR PROTEIN SYNTHESIS: A PERSPECTIVE
Z. P. Gates, N. Hartrampf
Pep. Sci. 2020, e24198. (link)
11. AUTOMATED FAST-FLOW SYNTHESIS OF ANTISENSE PHOSPHORODIAMIDATE
MORPHOLINO OLIGOMERS
C. Li,‡ A. J. Callahan,‡ M. D. Simon, K. A. Totaro, A. J. Mijalis, N. Hartrampf, C. K. Schissel. M. Zhou, H. Zong, G. J. Hanson, A. Loas, N. L. B. Pohl. B. L. Pentelute, (‡ = authors contributed equally)
Preprint on ChemRxiv (DOI: 10.26434/chemrxiv.12685886.v1, link)
10. DEEP LEARNING FOR PREDICTION AND OPTIMIZATION OF FAST-FLOW
PEPTIDE SYNTHESIS
S. Mohapatra,‡ N. Hartrampf,‡ M. Poskus, A. Loas R. Gomez-Bombarelli, B. L. Pentelute (‡ = authors contributed equally)
ACS Cent. Sci. 2020, 6, 12, 2277–2286 (link)
9. ULTRA-LARGE CHEMICAL LIBRARIES FOR THE DISCOVERY OF HIGH-AFFINITY
PEPTIDE BINDERS
A. J. Quartararo, Z. P. Gates, B. A. Somsen, N. Hartrampf, X. Ye, A. Shimada, Y. Kajihara, C. Ottmann, B. L. Pentelute
Nat. Commun. 2020, 11, 3183 (link)
8. SYNTHESIS OF PROTEINS BY AUTOMATED FLOW CHEMISTRY
N. Hartrampf, A. Saebi,‡ M. Poskus,‡ Z. P. Gates, A. J. Callahan, A. E. Cowfer, S. Hanna, S. Antilla, C. K. Schissel, A. J. Quartararo, X. Ye, A. J. Mijalis, M. D. Simon, A. Loas, S. Liu, C. Jessen, T. E. Nielsen, B. L. Pentelute (‡ = authors contributed equally)
Science 2020, 368, 980-987. (link)
Highlighted in a Science Perspective: C. Proulx, Science 2020, 368, 941 (link)
and by MIT News (link), Chemistry World (link), CE&N (link), Science Daily (link), Drug Target Review (link), Phys Org (link), the American Peptide Society (link) and others.
7. BTP-7, A NOVEL PEPTIDE FOR THERAPEUTIC TARGETING OF MALIGNANT
BRAIN TUMORS
N. von Spreckelsen, Y. Ghotmi, C. M. Fadzen, J. M. Wolfe, N. Hartrampf, C. Farquhar, S. Bergmann, M. Zdioruk, J. R. Wasserburg, E. Murrell, F. C. Bononi, L. G. Luyt, M. L. M. Lamfers, K. L. Ligon, E. A. Chiocca, M. S. Viapiano, B. L. Pentelute, S. E. Lawler, C.-F. Cho. BioRxiv: (link)
6. IMMUNE-MODULATING PHOTOCHROMIC GALACTOSYL CERAMIDES
ALLOW FOR OPTICAL CONTROL OF CYTOKINE PRODUCTION
Chem. Eur. J. 2020, 20, 4476 (link)
5. PROTEIN CHEMISTRY LOOKING AHEAD: 8TH CHEMICAL PROTEIN
SYNTHESIS MEETING 16-19 JUNE 2019, BERLIN, GERMANY
C. Bello, N. Hartrampf, L. J. Walport, A. C. Conibear
Cell Chem. Biol. 2019, 26, 1349-1354 (link)
4. TOTAL SYNTHESIS OF THE NORHASUBANAN ALKALOID
STEPHADIAMINE
N. Hartrampf, N. Winter, G. Pupo, B. Stoltz, D. Trauner
J. Am. Chem. Soc. 2018, 140, 8675-8680 (link)
Highlighted in Synfacts: E. M. Carreira, F. Pultar, Synfacts 2018, 14, 0898 (link)
3. LIGHT CONTROL OF L-TYPE CA2+ CHANNELS USING A DILTIAZEM
PHOTOSWITCH
T. Fehrentz, F. M. E. Huber, N. Hartrampf, T. Bruegmann, J. A. Frank, N. H. F. Fine, D. Malan, J. G. Danzl, D. B. Tikhonov, M. Sumser, P. Sasse, D. J. Hodson, B. S. Zhorov, N. Klöcker, D. Trauner Nat. Chem. Biol. 2018, 14, 764–767 (link)
Highlighted in Nature Chemical Biology News & Views: V. Vendrell, Nat. Chem. Bio 2018, 14, 749–750 (link)
2. SYNTHETIC APPROACHES TOWARDS ALKALOIDS BEARING ALPHA-
TERTIARY AMINES
A. Hager,‡ N. Vrielink, ‡ D. Hager, J. Lefranc, D. Trauner (‡ = authors contributed equally)
Nat. Prod. Rep. 2016, 33, 491–522 (link)
1. TARGETING A DYNAMIC PROTEIN–PROTEIN INTERACTION:
FRAGMENT SCREENING AGAINST THE MALARIA MYOSIN A MOTOR
COMPLEX
C. H. Douse, N. Vrielink, Z. Wenlin, E. Cota, E. W. Tate
ChemMedChem 2015, 10, 134–143 (link)
